Duska Separovic Selected Research

dihydroceramide desaturase

1/2017	Fumonisin B1 Inhibits Endoplasmic Reticulum Stress Associated-apoptosis After FoscanPDT Combined with C6-Pyridinium Ceramide or Fenretinide.
11/2014	Ceramide synthase inhibitor fumonisin B1 inhibits apoptotic cell death in SCC17B human head and neck squamous carcinoma cells after Pc4 photosensitization.
12/2013	Increased killing of SCCVII squamous cell carcinoma cells after the combination of Pc 4 photodynamic therapy and dasatinib is associated with enhanced caspase-3 activity and ceramide synthase 1 upregulation.
9/2013	Cationic ceramides and analogues, LCL30 and LCL85, as adjuvants to photodynamic therapy of tumors.
1/2013	Dihydroceramide desaturase knockdown impacts sphingolipids and apoptosis after photodamage in human head and neck squamous carcinoma cells.
7/2012	siRNA-mediated down-regulation of ceramide synthase 1 leads to apoptotic resistance in human head and neck squamous carcinoma cells after photodynamic therapy.
3/2012	Ceramide synthase 6 knockdown suppresses apoptosis after photodynamic therapy in human head and neck squamous carcinoma cells.

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Duska Separovic Research Topics

Disease

14	Neoplasms (Cancer) 01/2022 - 01/2011
10	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2016 - 01/2011
5	Squamous Cell Carcinoma of Head and Neck 01/2017 - 12/2013
2	Carcinoma (Carcinomatosis) 01/2018 - 09/2002
2	Carcinogenesis 01/2018 - 01/2017
2	Photosensitivity Disorders (Photodermatitis) 11/2014 - 07/2005
2	Lymphoma (Lymphomas) 05/2008 - 05/2004
1	Adenocarcinoma 01/2018
1	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2018
1	Colorectal Neoplasms (Colorectal Cancer) 01/2017
1	Head and Neck Neoplasms (Head and Neck Cancer) 01/2016
1	Breast Neoplasms (Breast Cancer) 02/2010
1	Leukemia 05/2008

Drug/Important Bio-Agent (IBA)

21	1-phenyl-3,3-dimethyltriazene (PDT)IBA 01/2022 - 09/2002
12	SphingolipidsIBA 01/2017 - 05/2004
11	CeramidesIBA 01/2017 - 07/2005
8	Photosensitizing Agents (Photosensitizers)IBA 05/2015 - 07/2005
7	dihydroceramide desaturaseIBA 01/2017 - 03/2012
5	silicon phthalocyanineIBA 05/2015 - 01/2013
5	SiliconesIBA 12/2013 - 01/2011
5	phthalocyanine Pc 4IBA 07/2012 - 07/2005
3	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 06/2014 - 06/2011
2	LCL521IBA 01/2022 - 01/2016
2	Acid CeramidaseIBA 01/2022 - 01/2016
2	Proteins (Proteins, Gene)FDA Link 01/2018 - 02/2010
2	fumonisin B1IBA 01/2017 - 11/2014
2	Caspase 3 (Caspase-3)IBA 01/2017 - 12/2013
2	FenretinideIBA 06/2016 - 05/2015
2	temoporfinIBA 06/2016 - 09/2011
2	EnzymesIBA 09/2013 - 05/2004
2	D- erythro- 2- N- (160- (1''- pyridinium)hexadecanoyl)sphingosine bromideIBA 09/2013 - 01/2011
2	Small Interfering RNA (siRNA)IBA 07/2012 - 05/2008
2	SuspensionsIBA 05/2012 - 09/2011
2	safingol (sphinganine)IBA 01/2011 - 09/2002
1	Formaldehyde (Formol)FDA Link 01/2018
1	Calcibiotic Root Canal SealerIBA 01/2018
1	DNA (Deoxyribonucleic Acid)IBA 01/2018
1	ParaffinIBA 01/2018
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2018
1	B7-H1 AntigenIBA 01/2018
1	A-factor (Streptomyces)IBA 01/2018
1	Protein Tyrosine PhosphatasesIBA 01/2018
1	Neurofibromin 1 (Neurofibromin)IBA 01/2018
1	MAP Kinase Kinase 1IBA 01/2018
1	TensinsIBA 01/2018
1	SphingomyelinsIBA 01/2017
1	SphingosineIBA 01/2017
1	Complement System Proteins (Complement)IBA 01/2017
1	VaccinesIBA 01/2016
1	retinamideIBA 05/2015
1	phthalocyanineIBA 12/2013
1	Dasatinib (BMS 354825)FDA Link 12/2013
1	sphingosine kinaseIBA 09/2013
1	N-palmitoylsphingosineIBA 09/2013
1	PorphyrinsIBA 09/2013
1	Dihematoporphyrin Ether (Porfimer Sodium)FDA Link 09/2013
1	AntibodiesIBA 05/2012
1	N-caproylsphingosineIBA 09/2011
1	CaspasesIBA 09/2011
1	CalciumIBA 09/2011
1	RNA (Ribonucleic Acid)IBA 05/2008
1	Superoxide DismutaseIBA 07/2005
1	Superoxides (Superoxide)IBA 07/2005
1	Serine C-PalmitoyltransferaseIBA 05/2004
1	Serine (L-Serine)FDA Link 05/2004

Therapy/Procedure

14	Photochemotherapy (Photodynamic Therapy) 01/2022 - 02/2010
5	Therapeutics 01/2022 - 01/2011